Scooby-Doo, the iconic Great Dane, made his debut in 1969 with "Scooby-Doo, Where Are You!" Created by Joe Ruby and Ken Spears, the series features Scooby and his friends solving mysteries involving supposedly supernatural creatures. Known for its humor and unique blend of horror and comedy, Scooby-Doo became a beloved franchise, spawning films, spin-offs, and merchandise.