In CSS, you can easily set the background color of an element using the "background-color" property. You can specify colors by name (e.g., "red"), HEX value (e.g., "#FF5733"), or RGB values (e.g., "rgb(255, 87, 51)"). For example: `div { background-color: #FF5733; }` applies a vibrant background to the div. Experiment with different colors to enhance your site's design.